tag:blogger.com,1999:blog-2467994117916260529.post7550290037583183546..comments2023-10-17T08:19:17.319-07:00Comments on Conditioning Research: Intermittent Fasting - for longevityChrishttp://www.blogger.com/profile/00223657383325055342noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-2467994117916260529.post-42263018481643160152008-07-02T12:33:00.000-07:002008-07-02T12:33:00.000-07:00Mikeinteresting piece here about IGF and GH and ca...Mike<BR/><BR/>interesting piece <A HREF="http://www.yourhealthbase.com/database/a109h.htm" REL="nofollow">here</A> about IGF and GH and cancer.Chrishttps://www.blogger.com/profile/00223657383325055342noreply@blogger.comtag:blogger.com,1999:blog-2467994117916260529.post-49321393957494859962008-07-02T12:29:00.000-07:002008-07-02T12:29:00.000-07:00Thanks donnyThanks donnyChrishttps://www.blogger.com/profile/00223657383325055342noreply@blogger.comtag:blogger.com,1999:blog-2467994117916260529.post-59387109494854075862008-07-02T12:19:00.000-07:002008-07-02T12:19:00.000-07:00Anonymous--I'll be a busybody and answer you about...Anonymous--I'll be a busybody and answer you about growth hormone. Growth hormone release wasn't blunted, it's effect was. The study calls it growth hormone resistance.donnyhttps://www.blogger.com/profile/02107555662488785352noreply@blogger.comtag:blogger.com,1999:blog-2467994117916260529.post-57602366983493790852008-07-02T12:14:00.000-07:002008-07-02T12:14:00.000-07:00I was just buzzing around looking for klotho and g...I was just buzzing around looking for klotho and growth hormone, to see if that path for longevity was similar and saw this study;<BR/><BR/>http://www.google.com/search?sourceid=navclient&ie=UTF-8&rls=SUNA,SUNA:2006-24,SUNA:en&q=klotho+growth+hormone<BR/><BR/>quote; "The klotho gene encodes a single-pass transmembrane protein that binds to multiple fibroblast growth factor (FGF) receptors and functions as a co-receptor for FGF23, a bone-derived hormone that suppresses phosphate reabsorption and vitamin D biosynthesis in the kidney."<BR/><BR/>It's a different numbered FGF, but hey.donnyhttps://www.blogger.com/profile/02107555662488785352noreply@blogger.comtag:blogger.com,1999:blog-2467994117916260529.post-85222093883462059262008-07-02T10:41:00.000-07:002008-07-02T10:41:00.000-07:00The linked to study specifies that the fast was 24...The linked to study specifies that the fast was 24hrs for mice -- on the surface that seems like an IF fast, but perhaps the mice to man translation makes it different?<BR/><BR/>If not, the curious thing about this is that it seems to go against the grain of other IF studies reported on this website that suggest that an IF fast *promotes* GH release. Hmmmm. What gives?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-2467994117916260529.post-74523392190297921622008-07-02T07:46:00.000-07:002008-07-02T07:46:00.000-07:00Interesting...but do we really associate "Starvati...Interesting...but do we really associate "Starvation" with IF? After all with IF there is no real calorie restriction or starvation response...so I doubt the mechanisms are the same. It may fit more along the lines toward long term CR therapy...but I think we have already seen that IF can provide the same results of CR without the negative side effects of starvation, loss of body composition (muscle) and well...starving. Still interesting thought on GH...as we need a healthy amount...but yes too much is never good as you can grow too much (gigantism) and also GH in a sick body only helps cancerous cells grow...which is not good. (why no one who has had or at risk for cancer before is allowed GH therapy)Mike OD - IF Lifehttps://www.blogger.com/profile/08988531038601012474noreply@blogger.com