Obesity and energy balance: is the tail wagging the dog?
We combine evidence from in vitro and in vivo experiments to formulate a perspective on obesity aetiology that emphasises metabolic flexibility and dietary composition rather than energy balance. Using this model, we question the direction of causation of reported associations between obesity and sleep duration or childhood growth. Our perspective generates new hypotheses, which can be tested to improve our understanding of the current obesity epidemic, and to identify novel strategies for prevention or treatment.
Does anyone have the full paper? UPDATE - thanks to the peopel that sent the paper including That Paleo Guy and Paul Jaminet. Thanks guys