First off, Vitamin D looks like it has potential here as often elsewhere:
- How Vitamin D Boosts Amyloid Beta Removal From Brain - which points to this at Eureka : scientists pinpoint how vitamin D may help clear amyloid plaques found in Alzheimer's
the early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein.Then this one which I don't fully understand (but thanks to Colin for sending it on)
Previous laboratory work by the team demonstrated that specific types of immune cells in Alzheimer's patients may respond to therapy with vitamin D3 and curcumin, a chemical found in turmeric spice, by stimulating the innate immune system to clear amyloid beta. But the researchers didn't know how it worked.
- Antibodies that block the process of synapse disintegration in Alzheimer's disease have been identified, raising hopes for a treatment to combat early cognitive decline in the disease -
neurons that were exposed to the antibody remained healthy, with no synaptic disintegration.
Dr Salinas said: "Despite significant advances in understanding the molecular mechanisms involved in Alzheimer's disease, no effective treatment is currently available to stop the progression of this devastating disease."
She added: "This research identifies Dkk1 as a potential therapeutic target for the treatment of Alzheimer's disease."