Sugar and cancer - more studies

I've had material on here before about the relationship between sugar and cancer. Cancer cells apparently rely on sugar to survive, so remove the sugar and you starve the cells. There have been experiments using ketogenic diets to treat cancer and other approaches using drugs to intervene down similar pathways.

I saw this in the New Scientist yesterday: Cancer's sweet tooth becomes a target

It is intersesting stuff.

Most of these efforts stem from an observation dating back to the 1930s - that cancer cells generate energy via glycolysis. This is different to the way cells normally make energy, through aerobic respiration in specialised chambers called mitochondria. Ordinary cells do use glycolysis but only if they are short of oxygen, as it is hugely inefficient, gobbling up large amounts of glucose for very little energy .

The focus is all on drugs though rather than diet

Comments

Chris D said…

Cancer cells don't rely on sugar to survive, that's a poor oversimplification of old research.

The by-products of glycolysis have some adaptive advantages for tumors, including angiogensis.

May 17, 2010 at 3:24 PM

pieter d said…

Chris,

In case you didn't see this already:

http://www.ted.com/talks/william_li.html

interesting, especially with your ancestral glasses on.

Pieter

May 18, 2010 at 1:21 AM

Dry January

I mentioned a few weeks ago that I was taking part in "Dry January". I didn't make a big song and dance about it, but I decided to go for a calendar month or so with no alcohol. A few people have asked me about my experience, so here are a few points. Why take a break from drinking? Alcohol is an interesting topic. As a drug it is widely accepted in society, central to so much of our socialising and leisure. There seem to be lots of health benefits - so we are told - yet there are also a lot of problems in terms of health, relationships and lifestyle that come from drinking. Over a few years I'd begun to become aware and then concerned that I was drinking too much and too regularly. I am in a busy and stressful job and sometimes a glass of wine after work to relax is really helpful. But over time, one glass became two. Two glasses became ....I might as well finish the bottle. A habit got established....and was starting to get too e...

So where have I been?

You will have noticed that this blog has been quiet for a while.... There are a few reasons for that, reasons that I thought I'd list here: WORK - my day job has been incredibly busy and stressful this year. Working 10-14 hour days the last thing on my mind when I got home was putting something on here. FACEBOOK/TWITTER - I suppose I've been using other channels to do some of what I used to do here. Quick fire posts pointing to interesting studies or news etc tend to get posted to Twitter (@chrishighcock) or to the Facebook Hillfit group http://www.facebook.com/groups/263083947097000/ REASSESSMENT - I've found myself less comfortable with some of the positions I've taken in the past. Sometimes I'm embarrassed by some of the things I've promoted. I'm not Paleo or low carb. I think Tabata and intervals are misunderstood and misapplied. I cannot really claim to be HIT. I find myselfunable honestly to post things on here and pretend that I am some sort o...

Taking up space for a brief update

I've a couple of posts in draft that I will get up soon - an update / reflection on Dry January and some thoughts on the scheduling benefits of short workouts if your life is busy. Before that though, I am pointing to something else. However, I wanted to highlight something that is coming this weekend that I've been involved in. Amber Rogers (Gokaleo and author of Taking Up Space ) has been pulling together a bundle of books from various authors with a common theme, one that I've been pushing here recently. Keep it simple, avoid the hype, be patient, be consistent and flee the gurus. I've talked before about how we get obsessed with pushing for more and more, when enough is OK. I've given my view that so much of the health and fitness internet world is more like a gnostic religion than something that will benefit your life. There are other voices out there saying similar things and I'll be pointing to a bundle of books later this week ...

Conditioning Research

Search This Blog