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Another excuse to drink red wine

What excuse do I need?

A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to control obesity, according to a Purdue University study.

It is an interesting mechanism here:

Kim found that piceatannol binds to insulin receptors of immature fat cells in the first stage of adipogenesis, blocking insulin's ability to control cell cycles and activate genes that carry out further stages of fat cell formation. Piceatannol essentially blocks the pathways necessary for immature fat cells to mature and grow.
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Comments

Nigel Kinbrum said…
Isn't that the opposite of what thiazoladinediones (diabetes drugs) do?

Stopping immature fat cells from maturing into fat cells may result in existing mature fat cells over-filling and spilling excessive amounts of NEFAs & glycerol into the blood.

Do not want.
April 4, 2012 at 3:58 PM
Chris said…
good point Nige
April 4, 2012 at 4:02 PM
Dan said…
My thoughts exactly. If you stop the fat from going into a new cell, where's it gonna go?? The other cells!
April 5, 2012 at 1:03 PM
John said…
Wait a second! ...Insulin has nothing to do with fat gain!
April 7, 2012 at 8:28 AM
Nigel Kinbrum said…
John, irony just doesn't work on the internets!
April 9, 2012 at 9:07 AM
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