Just skimming through these recent articles from the American Journal of Clinical Nutrition, you would think that refined carbohydrates are associated with:
loss of sight (updated 8/10/07...the Modern Forager blog has a good posting about this story); and
increases in the so-called "bad" LDL cholesterol.
Indeed, fructose is presented as a pretty dodgy thing to eat.
It is amazing that we are told to eat so many carbohydrates!