Saturday, June 16, 2012

Strength and insulin resistance

In all the discussions about how different diets may or may not promote insulin resistance, one thing that often gets missed out of the discussion is the role of the muscles.  Empty the muscles of glycogen through hard exercise and they will get more insulin sensitive to suck up the sugar out of the blood.  (Nigel has been trying to explain this but that is a different topic)

It is something that I talk about in Hillfit as a side benefit of strength training and an issue that Doug McGuff and John Little go into in Body by Science

Anyway, interesting to see this study come through this morning - at least some association between strength levels and markers of insulin sensitivity

Muscular strength and markers of insulin resistance in European adolescents: the HELENA Study

The aim of the study was to examine the association of muscular strength with markers of insulin resistance in European adolescents. The study comprised a total of 1,053 adolescents (499 males; 12.5–17.5 years) from ten European cities participating in the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) Cross-Sectional Study. Muscular strength was measured by the handgrip strength and standing long jump tests. Cardiorespiratory fitness was measured by the 20-m shuttle run test. Fasting insulin and glucose were measured and the homeostasis model assessment (HOMA) and quantitative insulin sensitivity check index (QUICKI) indices were calculated. Weight, height, waist circumference and skinfold thickness were measured, and body mass index (BMI) was calculated. In males, the handgrip strength and standing long jump tests were negatively associated with fasting insulin and HOMA (all P < 0.05) after controlling for pubertal status, country and BMI or waist circumference. When skinfold thickness was included in the model, the association became non-significant. In females, the standing long jump test was negatively associated with fasting insulin and HOMA (all P < 0.001) after controlling for pubertal status, country and surrogate markers of total or central body fat (BMI, waist circumference or skinfold thickness). Findings were retained in males, but not in females after controlling for cardiorespiratory fitness. The findings of the present study suggest that preventive strategies should focus not only on decreasing fatness and increasing cardiorespiratory fitness but also on enhancing muscular strength.

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